before. Others have only a very flight fit in the winter, which feldom continue fo long as a week; whereas, before the opening of iffues, moft of them were laid up with the gout fome months every year; among whom there were two much incommoded with humours of chalky matter on fome of the joints, who are now free from that inconveniency; thefe humours having fuppurated and difcharged their contents by little and little, fo that the ufe of fome joints was recovered, after having been bound up by these tumours for fome time. This to me feems to be a proof that the fupply of humours, which formed thefe tumours, was cut off by the difcharge of the iffues, and confequently proves the preventive efficacy of them, by draining off the gouty matter, which would otherwife be accumulated,after fome time, to a quantity fufficient to caufe a fit or fits. I have always ordered thefe openings to be made above the knee, immediately above the gartering place, which I have found to be a more convenient part for iffues than below the knee. I am also convinced, from experience, that thefe drain in the lower extremities are particularly beneficial, (by giving a direction of the humours downwards) in preventing the gout from affecting the head, breaft, and ftomach; a relief from the apprehenfion of which is generally very confolatory to every perton threatened with that difcafe in thefe parts; even this advantage alone feemed to me a fufficient inducement for the ufe of them, and was my first motive to the trial of them, on one of my patients, in imminent danger, from the gout in the head and breaft; in which cafe they gave fuch relief as engaged me to order them for thofe of my patients who were the most afflicted with this difeafe. I have generally found that one iffue is fufficient to carry off or prevent the difeafe, except the fits are long, frequent and violent; in fuch cafes I always defire that two issues may be opened. I imagine that every body will easily be convinced of the neceflity of fuch outlets in gouty bodies; and, I hope, that the benefit of them will be found on trial; their ufe is become fo general here, that even the porters, almoft to a man, have iffues either in their arms of legs, and they find much benefit from them, for old achs from strains and for rheumatic and feiatic pains. Though I know of no objection which can be made to the opening of iffues for the gout, notwithstanding I advife every person to confult the phyfician, who is beft acquainted with his constitution before he takes this fiep; perhaps fome extraordinary circumftance may for bid the ufe of them. As I have no other motive or view, in making this public, but that of the relief of thofe afflicted with the gout, I only beg the fa vour of those who try this method of cure, that they tranfmit to me an account of its effects for my further information. Letters may be directed to Dr. Turnbull, in Smyrna, to be left at the Swordblade Coffee-houfe, London. Poft paid to London. I am, Sir, your most humble, and most obedient fervant, A. TURNEUIL. P. S. I intended to have wrote more fully on this method of carry It is, I believe, twelve or fourteen years fince I first perceived a pain, uneafinefs, and weight in my left kidney, which gradually increafed till it made my life very uncomfortable. As I had known Mrs. Stephens's medicines to have been very fuccefsful in many fuch cafes, I applied to her, and took her remedies for fome years, and found myfelf much better and easier for them while I continued them, but whenever I left them off for any time, I had a conftant return of the fame complaints. Upon this I left them quite off, and tried several other things which were recommended to me, and generally found ease upon the first trial of every new medicine, but after leaving it off for any little time, my old complaints returned again. It is now above a year ago fince I left off all these medicines, and took to lemon juice and water, with a little fugar, for my conftant drink. I continued this method for near a year with fome intervals, ufing two or three, and fometimes in hot weather, four lemons every day. And I found myfelf grow daily eafier, fo that for many months I have had fcarce any uneafinefs in my kidney; and about fix weeks ago I had a great forcing to make water, when a kind of jelly came from me, which, upon examination, feemed to be the gluten, which probably connected together the folid parts of a stone. I think it is the general opinion of our phyficians, that a ftone in the human body confifts of earthy parts, with a little alcaline falt and air, which are connected together by a gluten or glue; and that the alcaline medicines, fuch as foap and lime, diffolve this glue, by which means the earthy parts feparate from the reft, and come away infenfibly, but that acid medicines diffolve the earthy, &c. parts of the ftone, ed. and leave the glue untouchAnd Dr. Lobb in his treatife on diffolvents of the ftone, fhews us by experiments, that lemon juice will foften, and even diffolve a ftone. I blefs God I am now quite eafy, and happy, and am fully fatisfied that I have got rid of a fione which gave me fo much uneafinefs for many years; and which, if I may judge by the largenefs of the glue which came from me, I believe was of the fize of a large Spanish nut. The remedy I ufed was very pleafant and agrecable to me, efpecially in the fummer. I gene. rally fqueezed the juice of a large lemon 4 lemon into a little above half a pint of foft water, and fweetened it to my tafte; and whenever I was faint, or it was cold at my ftomach, I added a little white wine to it. It never gave me the cholic, which I find lemons do to fome perfons, to whom, therefore, this remedy would be very improper. If, upon this faithful narrative of my cafe, any perfons fhould try it and be cured, I hope they will be fo good as to acquaint the public of it, that it may encourage others to try it. MY Y diforder has neither confined me an hour at home, nor kept me any night from quiet fleep. When I perceived the symptoms of a stone in my bladder, I returned to the use of the coffee. And on the account of my bloody water, I ordered my fervant firft to make a tea with ground-ivy. nd then to make my coffee with that tea, which rendered the flavour to me more agreeable: I put about one Spoonful of milk to a quarter of a pint dith of coffee, and made it very fweet to my palate; I drink three dishes at breakfaft, and two in the afternoon. This liquor, we call coffee, as I have obferved, does not ftimulate as a diuretic, nor occafion a palecoloured urine like water, but all the proper contents of urine come off with it. When fuch a pale urine happens, the liquor before drank was improper for the perfon, or was taken in too large a quantity. This is commonly the cafe when diforders in the paffions of the mind did not precede. It is a good rule for every man's obfervance, viz. to avoid fuch li quors as occafion a colourless urine, or to drink them in lefs quantity. My drink at dinner is about half a pint of New-river water, with the juice of one lemon, and well fweetened with fugar. While my pains were very fharp, as well as frequent, I took half a common spoonful of a mixture made with four ounces of honey, and one ounce of the oil of olives. I have carefully avoided all ftimulating diuretics, and have used as much as convenient thofe forts of aliment which have a diffolvent quality. Through many months past, I have made no bloody water; and from this alteration in my cafe, and from the abatements of my other fymptoms, I would hope that the tone in my bladder is lefs, though it is not gone. I will only add, that it will give me a great fatisfaction if this paper proves beneficial to any that fhall read it. The Hypericum Campodarense the gentlemen called to perfors of Columna, recommended to trial who had taken corrofive fublimata as a powerful vermifuge. By mercury, and whofe cafes w Dr. Hill. have feen from time to time pblifhed. Common fea-falt, diffolved ADOG to whom Dr. Hill had given a dram and a half of the glandular part of the cups of the Hypericum Campodarenfe of Columna, voided after a few hours, a flat worm, of a vaft length. This was evidently occafioned by the herb; but whether it will difcharge the common round worms, as well as the flat, and whether it will take effect in humane, as well as brute bodies, are points yet to be determined by experience. Phyficians, who feek the good of mankind, are requested to try. The plant is perfectly fafe and wholefome; and the virtues of the genus to which it belongs, in this way, are not unknown, though they have been overlooked. Bartholine has recorded the common Hypericum as a remedy against worms, with the title of prestantissimum; and Camerarius, long before, had celebrated it for the fame purpofe: after a trial of that kind, which feems too weak for the purpose, this fpecies was chofe, because of its evidently greater ftrength; the fcent being more refinous, and the glands of the cup, in which the principal virtue refides, vaftly larger, and more prominent. The plant is a native of England, though not common; and may be easily raised in any quantity, if its virtues are found by more experience to deferve it. Account of some antidotes against corrosive sublimate mercury. T is furprising the advantage of falts never occurred to any of ους y in the water which the pants Volatile and fixed alkaline s and fpirits alfo precipitate mor fpirits of falts of bartthorn, cri ammoniac, falt of tartar and wornwood, &c. but as thefe can fakem be got on a fudden, the follow articles may be used: pot-afheilfolved in warm water (or cold : E fome can be got warm) fo as not to be too acrid. Failing thefe, frain warm water through afhes of beanftalks, broom, afh, or any other plant that can be fooneft burnt: white and black foaps, containing thefe falts and oil, are very fit to be melted in all the water drank, or injected by way of clyfter. If none of thefe can be got, or in fome cafes thought not proper, any of the tefiacea, crabs eyes, crabs claws, fhells of oyfters, muscles, or eggs, coral prepared, or common chalk pounded or fcraped into their drink, will precipitate the mercury; and as fome of them. at the fame time add a mucus to the excoriated flomach and inteftines, they may be used with advantage at least. As one or feveral of the above articles can easily be got, even in the country, your publishing this may fave the lives of fome, which otherwife would be loft. The The falts ought to be ufed at firft, fo long as the vomiting and purging is to be continued: then oils, butter, fat broth, drank and injected, to comfort and foften thefe parts, after fo much violence. Cautions against the use of seggs. AVING frequently feen children at playwith feggs in their mouths, by blowing them, in order to make a noife; and others upgrown, who have used the juice thereof, for curing of the toothach; I hope an obfervation on its deleterious effects, will not be unacceptable to the publick, as it will give them a caution against its internal ufe. One Sufannah Lindley, a girl aged 14, fnuffed up her noftrils (in imitation of fome, who had done' fo for the tooth-ach) the quantity of a thimble-full of the juice of the root of the common fegg, about 3 o'clock in the afternoon of the 18th inftant; and within half an hour after, began to be affected with a burning pain in her noftrils, and up to her head. By-and-bye the felt her arms and legs becoming benumbed, and the heat, &c. in her noftrils to increafe; which continued until five o'clock, when her legs and arms became contracted, stiff, and stretched out, with much pain. She continued thus convulfed for about half an hour, and then her contractions went off; nevertheless the extremities were very cold, and the fill complained of a painful heat in her head and noftrils, until feven o'clock, and then her right knee began to flake most violently, and the feemed in general to be growing worfe. Whereupon they had fome advice, and were ordered to have fome warm milk and water fyringed up her noftrils, as foon as poffible, in order to wash off the juice that full adhered to the membranes thereof. But before they could get this done, fhe fell into another fit the fame as before; yet was inftantly better, upon their throwing up the injection, and, after repeating it about eight or ten times, the limbs perfectly relaxed, the pulfe became regular, and the extremities recovered their natural heat. About an hour after this fhe went to bed, flept well, and in the morning only complained of a flighti pain and heavinefs in her head, which went quite off in the next night's fleep, and he has now continued quite well these feveral days paft. March, 1761. Method of curing luxations of the spine, or broken backs. HIS difeafe has been fometimes held to be incurable, not only by the ancient, but by the more expert modern furgeons too; but with how little reafon, may appear from the following cafe, abridged from Bonetus's Medicina Septentrionalis Collectitia.p. 603. Three vertebræ of the loins were dislocated, or forced inward, with total lofs of fense and motion in all the parts below. The cure was performed by extenfion, with cloths or fwaths under the arms and about the thighs; the former drawn by men, and the latter by a machine in another room, till the cracking bones gave notice that the extenfion was enough. The bones then being fet, and the extension gradually leffened, the motion of fome parts returned prefently, and of all parts, |